Guardian may refer to:
- Guardian Units of Nations (aka G.U.N.)
- The Stone Guardian, sub-boss of the Sandopolis Zone in Sonic & Knuckles.
- The Babylon Guardian from Sonic Riders
- Lazaar's Guardian, from the Sonic the Hedgehog episode "Super Sonic"
- Guardian (title), the title most commonly given to the echidna protectors of Angel Island.
- Guardian Robot, from Sonic the Comic
- Dark Guardian, a boss from Sonic Unleashed