She is well known for voicing many characters in many anime shows, including Soifon and Momo Hinamori in Bleach, Rider in Fate/Stay Night, Kallen Stadtfeld-Kozuki in Code Geass, Fasalina in GUNxSWORD, Mahiro Muto in Buso Renkin, Fantine Valjean in IGPX. She also does voices for other Japanese video games, including Aigis in Shin Megami Tensei: Persona 3 FES and Nanako Dojima and Izanami-no-Okami in Shin Megami Tensei: Persona 4, and Carmilla in Castlevania: Judgment.
Her performance has received positive to mixed reviews. Many fans praise her voice as being sexy, and higher-pitched like Rouge's previous voice actress, Lani Minella. Some fans have said her voice is the most suitable for a girl of Rouge's age, but others have felt that she makes Rouge sound too promiscuous.
Strassman has lent her voice in Mortal Kombat 9 voicing Kitana and Mileena, in which she worked with Lani Minella.
Strassman is also the current voice of infamous Capcom character Poison as of Street Fighter x Tekken. Like Rouge, Poison was previously voiced by Lani Minella.