Mario and Sonic may refer to:

• Mario and Sonic, two notorious video game icons.
• Mario & Sonic series, a series of cross-over video games starring these characters.
• Mario & Sonic at the Olympic Games, the first official cross-over game between the two characters.
• Mario & Sonic at the Olympic Winter Games, the second title in the Mario & Sonic series.
• Mario & Sonic at the London 2012 Olympic Games, the third title in the Mario & Sonic series.

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