Slicer may refer to:
- Slicer, the enemy that appears in the Sonic the Hedgehog video games.
- Slicer (Sonic the Comic), the character in the Sonic the Comic series published by Fleetway Editions.
- Slicer (Archie), the character in the Sonic the Hedgehog comic series and its spin-off published by Archie Comics.
- Slicer (Pre-Super Genesis Wave), the version of the Slicer before the Super Genesis Wave.